Anti-aging Growth Factors for Skin Care
ANTI-AGING GROWTH FACTORS
The largest organ on the body is the skin. It includes the outer covering that covers the internal organs providing protection from viruses, bacteria and other foreign bodies. It is also essential in making vitamin D as well as being integral in heat regulation, sensation and of course aesthetics.
Skin is the most visible indicator of a person’s health, moods and even age. For instance, a person who is scared or cold will show visible goose bumps. This outer cover to the human body is what gives us our looks. Good-looking skin inevitably means a better looking individual. As expected, there are thousands of skin care products in existence that promise radiant and ageless skin.
As we age, skin changes are inevitable. Cell regeneration slows down with age and this is also true for skin cells. Since the skin is at the mercy of many destructive forces such as the sun, bad habits and injuries, time eventually begins to show on it.
The following changes naturally occur on the skin with age:
• Skin becomes rougher.
• Skin develops lesions such as benign tumors.
• Skin becomes slack. The loss of the elastic tissue (elastin) in the skin with age causes the skin to hang loosely.
• Skin becomes more transparent. This is caused by thinning of the epidermis (surface layer of the skin).
• Skin becomes more fragile. This is caused by a flattening of the area where the epidermis and dermis (layer of skin under the epidermis) come together.
• Skin becomes more easily bruised. This is due to thinner blood vessel walls.
• The vascular supply to the skin wears down, leaving the skin dry due to less oxygen and nutrient supply.
The new frontier in regenerative and anti-aging skin care is the use of growth factors. Advanced biotechnology firms like Stem Cell 21 are pioneering the research and use of stem cell therapy and growth factors in skin care and anti-aging therapies.
What Are Growth Factors?
Every cell in your skin secretes proteins known as growth factors. Growth factors are natural proteins in your body responsible for a variety of cellular activities such as growth, proliferation and differentiation. They play an integral role in maintaining healthy skin function and structure.
Growth factors act as natural messenger proteins that allow communication between cells in our body. They are the control mechanism for all wound healing. One way in which they work is by repairing skin that is damaged from natural aging. As we age, our bodies produce lower levels of natural growth factors resulting in more breakdown of collagen. This is important for us, because collagen is the foundational support to the skin.
Many types of growth factors can be cultured from the skin each with its own unique uses and properties as follows:
• Basic fibroblast growth factor (BFGF): It is essential in prenatal and postnatal growth and development and also regeneration of a variety of tissues by helping further progress in cellular differentiation due to its growth factors.
• Epidermal growth factor (EGF): This protein is found on the surface of some cells. It is involved in normal cell growth and plays an important role in cell lineage determination and wound healing. This is done through the stimulation of epidermal and dermal regeneration.
• Fibroblast growth factor (FGF): The function of FGFs is not limited to cell development. They are powerful regulators of cell differentiation, function and proliferation and are also significantly vital in development, tissue maintenance and wound repair.
• Hepatocyte growth factor (HGF): The HGF is a major growth factor which regulates both cell growth and cell motility.
• Keratinocyte growth factor (KGF): It protects different types of epithelial cells from various harmful factors and it is important in protecting and repairing injured epithelial tissues.
• Transforming growth factor-beta (TGF-β): These are important in cell growth and development, inflammation and repair, and host immunity.
• Vascular endothelial growth factor (VEGF): Helps to promote and stimulate the growth of new blood vessels.
• Brain-derived neurotrophic factor (BDNF): This growth factor’s function is to promote the survival of nerve cells. It does this by playing a role in the growth, differentiation and maintenance of the nerve cells.
• Insulin-like growth factor (IGF): The IGF plays a crucial role in the regulation of growth and metabolism.
• Platelet-derived growth factor (PDGF): It is yet another growth factor that regulates cell growth and division and plays an essential role in healing wounds.
How Growth Factors Work
We are all born with growth factors. As we age, the production of these growth factors reduces which takes a toll on the skin. Fortunately, growth factors can now be cultured from human and plant stem cells. To know more about stem cells and all their wonderful benefits, you can take a quick tour here. These growth factors can then be introduced into serums, creams and lotions.
Regenerative medicine teams carry out initial assessment that examines the skin and determine which growth factor is appropriate. Stem cells are then harvested and used to synthesize the desired growth factor.
One of the benefits of using growth factors as anti-aging treatment is the growth factors can come from the individual that is to use them. This eliminates the minor risk of side effects since the cells used are one’s own. The procedure is safe, sterile, simple and can be completed in a few hours.
The extracted sample then undergoes a process to culture the growth hormones in a centrifuge. This separates and purifies the cells which are now ready to be added into skin care products for application.
This high concentration of cells makes an effective anti-aging serum ready to battle the wrinkles, line and discolorations that become more evident as we grow older. This system is suitable for all skin ages and types.
Once the growth factors, each with a specific message, are applied to the skin, multiple messages get into play at any time in an Mesenchymal Stem Cells (MSCs) mediated response. The messages are tightly coordinated to enable them reach the right cells at the right time, for the proper work to be done. Some are very short distance and some are medium or long distance. MSCs themselves can differentiate into needed cells for rebuilding damaged tissue.
As the growth factors continue acting in the skin after they are introduced to the skin, and begin to multiply, patients will notice:
• Positive difference in energy levels
• Reduced fatigue, enhancement in muscular strength
• Reduced fine lines and wrinkles on skin
• Rejuvenated aged and sun-impaired skin
• Reduced hyper-pigmentation marks
• Removal of marks and scars left by acne, rosacea, and chicken pox
Safety And Efficacy Of Growth Factors
Growth factor skin care products have the power to penetrate deep into the skin’s many layers and regenerate old and dormant cells naturally and restore the skin to a healthier, younger appearance. The bioengineering process used to create growth factor skin care products makes them stable enough to continue acting on the skin for a long enough period after application.
Since growth factors are just cells that already exist normally in the body, they cause no harmful effects when used. Growth factor use is basically a re-introduction and replacement of depleted skin regenerating proteins.
The use of growth factors should ideally coincide with a conscience reduction of factors that increase skin aging. One should reduce the following factors that hasten skin aging:
• Sun: the sun plays a major role in prematurely aging our skin. To avoid this, one should protect their skin from sun exposure every day. You should apply sunscreen to all skin that is not covered by clothing. Sun damage causes wrinkles and permanent damage of skin causing appearance of age spots, wrinkles, reduction in skin elasticity and sagging skin.
• Cold: spending a lifetime in cold environments causes the skin to appear too thin and wrinkles to develop.
• Weight: being too skinny or heavy adds to the aging process. Being underweight reduces the natural fats in the facial structure, causing the appearance of wrinkles. Too much weight on the other hand can also make us look older by creating poor muscle tone.
• Alcohol is rough on the skin. It dehydrates the skin causing damage to the skin texture and color. Heavy drinkers begin to have facial skin that is discolored over time, leaving permanent marks on the body. Drinking excessively also has considerable influence on the eye sockets.
• Smoking greatly speeds up how quickly skin ages by causing one to have wrinkles and a dull, sallow complexion.
• Repetitive facial expressions: it is recommended to avoid repetitive facial expressions. If you repeatedly contract the same muscles for many years, these lines become permanent.
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